The 49ers are 5-6-0 lifetime against the Bills

1972	Bills 27-20 (@Buf)
1980	Bills 18-13 (in SF)
1983	49ers 23-10(@Buf)
1989	49ers 21-10 (in SF)
1992	Bills 34-31 (in SF)
1995	49ers 27-17 (in SF)
1998	Buffalo 26-21 (@Buf)
2001	35-0 (in SF)
2004	Buffalo 41-7 (in SF)
2008	10-3 (@Buf)

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